The 
enthalpy of neutralization (
ΔHno) is the change in 
enthalpy that occurs when an 
acid and 
base undergo a 
neutralization reaction to form 
water and a 
salt. It is a special case of the 
enthalpy of reaction.
When a reaction is carried out under 
standard conditions at the temperature of 298 K and 1 
atm of pressure, it is called the 
standard enthalpy of neutralization.
The heat (
Q) released during a reaction is
- Q = m c ΔT
where 
m is the mass of the solution, 
c is the 
specific heat capacity of the solution, and ∆
T is the temperature change observed during the reaction. From this, the standard enthalpy change (∆H) is obtained by division with the amount of substance (in 
moles) involved, usually the amount of H
+ ions:
- ∆H = - Q/n
The standard enthalpy change of neutralization for a strong acid and base is -57.3 kJ/mol.
The standard enthalpy of neutralization for mineral acids is far greater than that of organic acids, because strong acids ionize completely while organic acids are usually weak and ionize only partially.
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